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Contact your GP, practice nurse, or NHS 111 if you experience concerning symptoms, including: Severe or persistent abdominal pain, especially if radiating to your back (may indicate pancreatitis) Persistent vomiting preventing fluid intake Signs of hypoglycaemia (shakiness, confusion, sweating, rapid heartbeat) Severe injection site pain, swelling, or signs of infection Symptoms of gallbladder problems (pain in upper right abdomen, fever, yellowing of skin/eyes) Signs of allergic reaction (rash, swelling, difficulty breathing) Call 999 if you experience severe allergic reaction symptoms or severe, sudden abdominal pain with vomiting