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Indeed, BMSCs exposed to exendin-4 showed increased gene expression of the bone transcription factors Runx and Osterix and bone matrix-producing genes Balp and Bglap
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In our experiment of endothelium-dependent vasodilation, 10 −9 –10 −7 mol/L acetylcholine (Ach) stimulation decreased the vascular tension of aortic rings in a dose-dependent manner in wild-type mice under normal diet condition (Fig