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The phase 3 SYNCHRONIZE-1 trial (NCT06066515) randomised 726 adults with obesity, or overweight with at least one obesity-related complication, and without type 2 diabetes, of whom 725 received treatment, to weekly injections at 3.6 mg or 6.0 mg, or placebo
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Future research should examine whether similar findings apply to: People using GLP-1 drugs primarily for obesity Younger adults Individuals without diabetes Patients taking GLP-1 medicines for emerging indications, such as fatty liver disease or addiction What This Means for You GLP-1 medications remain highly effective treatments for obesity and type 2 diabetes, with well-established benefits for weight loss and blood sugar management
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