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The molecule was rationally designed by Eli Lilly scientists to simultaneously engage three G-protein-coupled receptors central to metabolic homeostasis: the glucose-dependent insulinotropic polypeptide (GIP) receptor, the glucagon-like peptide-1 (GLP-1) receptor, and the glucagon receptor
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Urgent medical care is appropriate for severe or persistent upper abdominal pain, especially if it spreads to the back or is accompanied by vomiting, because this may suggest pancreatitis
