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Critically, the data dismantles the long-standing narrative that frames data integrity lapses and inadequate investigations as a problem intrinsic to “emerging markets.” The 2025 warning letters show that Western manufacturers—operating under mature regulatory frameworks and advanced technological infrastructures—are equally susceptible to the same failures
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Keywords: Type 2 diabetes mellitus, GLP-1 receptor agonist, SGLT2i inhibitor, Glycemic control, Cardiovascular disease PATHOPHYSIOLOGY OF TYPE 2 DIABETES MELLITUS (T2DM) The Triumvirate In 1987 our understanding of the pathophysiology of type 2 diabetes mellitus (T2DM) was relatively simple and referred to as the TRIUMVIRATE (1)
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