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Qsymia contains phentermine, so it works the same way, but it also contains the active ingredient topiramate, which is thought to work by suppressing appetite and increasing feelings of fullness
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Data availability The atomic coordinates and the cryo-EM density maps generated during this study are available at the protein databank ( and the electron microscopy databank ( under accession numbers XXXX and XXXX, and EMDB entry ID EMD-XXXXX and ID EMD-XXXXX for the semaglutide and taspogltuide complexes, respectively