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GLP-1, GIP, and dual agonist medications are all part of the incretin class. But they are not interchangeable. GLP-1 receptor agonists like semaglutide reduce appetite, slow digestion, stimulate insulin, and suppress excess
27 Thus, the GLP-1 RAs directly exert dual benefits: through their anti-inflammatory and neuroprotective mechanisms, and by improving metabolic variables that worsen headache burden
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