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GLP-1 receptor agonists got their start in an unlikely place: the mouth of a lizard. A peptide discovered in Gila monster saliva, called exendin-4, was found to mimic the action of GLP-1

These results were attributed not just to improved glycemic control, but to anti-inflammatory effects on arterial walls, reduced plaque formation, and enhanced endothelial function

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Put the needle through the rubber top of the vial and push the plunger to inject the air into the vial