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Many patients taking GLP-1 medications (including Ozempic, Wegovy, Mounjaro, Zepbound, Rybelsus, Trulicity, Saxenda, and Victoza ) experienced rapid weight loss, severe abdominal pain, ER visits, and ultimately surgery
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The signaling pathways involving NMDA receptors and glutamate have been associated with obesity in human genomic studies, further reinforcing the rationale behind this pharmacological strategy