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Time-to-onset analysis Time-to-onset (TTO) was defined as the interval between the AEs onset date (EVENT_DT in DEMO file) and start date of semaglutide use (START_DT in THER file) ( Results Descriptive analysis During the study period, a total of 6,437,182 AE reports were obtained from the FAERS database after exclusion of duplicates, containing 11,326 semaglutide-related gastrointestinal AEs in 5,442 patients
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