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Ultra-rapid metabolizers: Increased CYP2D6 activity leads to faster metabolism of Adderall

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Led by Lorenzo Leggio, MD, PhD of The National Institute on Drug Abuse (NIDA) and the National Institute on Alcohol Abuse and Alcoholism (NIAAA), the research outlines how activation of GLP-1 receptors in the brain may modulate reward circuits involved in substance craving and dependence