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A New Drug Combines Five Targets in One Molecule to Combat Obesity and Diabetes- and It Outperforms Ozempic in Mice

Together, these results reveal that obesity-induced changes in beta-cell function may parallel or follow, rather than precede, increases in alpha-cell number, suggesting that alpha-cell proliferation may serve as a pro-active, as opposed to reactive, response to metabolic dysfunction ( Figure 4 )

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Weiser et al., 2008)