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However, 'most people' is misleading because individual tolerability depends on genetics, starting dose, titration speed, and concurrent health conditions rather than the medication itself
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For example, scientists theorize that GLP-1 receptor agonists like semaglutide interact with neurons located in the arcuate nucleus of the hypothalamus and upregulate the expression of proopiomelanocortin/cocaine- and amphetamine-regulated transcript (POMC/CART) [12]
