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22 Eli Lilly and the Tirzepatide Portfolio: Manufacturing as a Moat While Novo Nordisk has focused heavily on the longevity of a single molecule, Eli Lilly’s strategy for tirzepatide (Mounjaro and Zepbound) is defined by clinical differentiation and an aggressive “manufacturing moat”

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Specifications Retatrutide is a synthetic peptide engineered as a balanced agonist at three metabolic receptors simultaneously: GIP, GLP-1, and glucagon