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GLP-1 medications like semaglutide and tirzepatide are on the rise, but so are accidental overdoses of these medications. Poison control centers have seen a massive surge in calls regarding weight-loss and diabetes

This systemic anti-inflammatory effect of TLR agonist-induced inflammation of central GLP-1R is mediated via the α-adrenergic, δ-opioid, and κ-opioid receptor signaling pathways (Wong et al., 2024)

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