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However, these agents are associated with increased thyroid cancer risk, and the packaging for these medications in the United States has a boxed warning stating that they are contraindicated in people with a personal or family history of medullary thyroid cancer and in patients with a diagnosis of multiple endocrine neoplasia syndrome type 2
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This study simulated the weight reduction effects of the drugs across three age groups (45, 55, and 60 years)
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