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The STEP trial program, which included over 4,500 patients, demonstrated that semaglutide 2.4 mg once weekly combined with lifestyle intervention produced an average 15% body weight reduction over 68 weeks, compared to 2.6% with placebo
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Odorranalectin-conjugated PEG-PLGA NPs (OL-NP) have successfully transported macromolecules such as urocortin into PD animal models via the intranasal route, enhancing neuronal survival and attenuating disease progression [295]
