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This molecule is designed to integrate NMDA receptor antagonism with glucagon-like peptide-1 (GLP-1) receptor agonism, successfully reversing obesity, hyperglycemia, and dyslipidemia in rodent models
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Researchers study cyclic adenosine monophosphate (cAMP) production, protein kinase A (PKA) activation, β-arrestin recruitment, receptor trafficking, phosphorylation cascades, and transcriptional regulation