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Among individual GLP-1 RAs, exenatide exhibited the longest median time to onset at 45 days (IQR = 11–213 days), while dulaglutide had the shortest at 7 days (IQR = 2–9 days), liraglutide at 16 days (IQR = 5.5–61 days), semaglutide at 12 days (IQR = 4–45.5 days), and tirzepatide at 10 days (IQR = 2–35.5 days)
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